Neuropeptide Y (3-36) (porcine)

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Neuropeptide Y (3-36) (porcine) 是神经肽 Y (NPY) 受体 Y2 亚型的激动剂，但通过另一种未知受体介导大鼠摄食。

Neuropeptide Y (3-36) (porcine) is an agonist of neuropeptide Y (NPY) receptor subtype Y2, and stimulates feeding in rats. Neuropeptide Y (3-36) (porcine) is a highly Y2 selective ligand compared with nselective Y1/Y2 receptor ligand, Neuropeptide Y 1-36.

Neuropeptide Y (3-36) (porcine) (0.24-24 nM; i.c.v.; single dose) induces feeding in the rat in a dose-dependent manner. Neuropeptide Y (3-36) (porcine) (4 μg, 8 μg; i.c.v.; single dose) significantly increased food intake at 2 and 3 h, results dose-dependently orexigenic effect in rainbow trout (Oncorhynchus mykiss).Animal Model:Adult male Wistar rats (250-300 g) Dosage:0.24, 0.72, 2.4, 7.2, 24 nM per animal Administration:Intracerebroventricular injection; single dose Result:Stimulated rat feeding dose-dependently.Produced no feeding effect alone, that Y2 activation alone elicited no feeding response.

Neuropeptide Y (3-36) (porcine) accounts for 35% of NPY-like immunoreactivity in porcine brain.? Neuropeptide Y (3-36) (porcine) shows high affinity for Y2-like receptors on CHP234 cells, andlight affinity Y1-like receptors on SK-N-MC cells.

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Others

Other Targets

NPY Y2 receptor

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143863-88-1

3993.4

C176H271N53O54

>98% (HPLC)

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(-20℃)

With Ice Pack

≥ 2 years